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Experts from Brigham Young University in Utah found that addiction is a result of an 'overcorrection' inside brain, a PsychCentral report said. Using two separate drugs to shed weight can be very effective you can find combinations while watching FDA now awaiting approval. When dealing with fat loss and the people that go through it one should err assisting caution and let the FDA do its job and demand some investigation be done so that the public is aware of the side effects and dangers of the medications before we drive them. Keep in mind that drug companies have been in business to earn money and that they would say anything to keep people on the medications. Researchers found that participants using this drug to get a year, lost weight within four weeks and have kept the load off through the entire 56 weeks from the study. Contrave is often a combination with the drugs naltrexone and bupropion, which appears to reflect a whole new trend of weight-loss drugs which are made up of many active ingredient, that might make them more effective and safer. Combo-pilling could be the newest fad or also the newest ahead under scrutiny and thus it is just more publicly known recently, comb-pilling for losing weight has been around since the eighties. The biggest reason that employing a combination of pills is starting to become popular will be the fact that at the time of right now there aren't long term prescription weight loss supplements that have been authorized by the FDA other than orlistat. The truly disturbing part is always that doctors are prescribing these combinations of medications and some of the combinations are already rejected or have yet to be approved by the FDA. Seizures can be a side effect with Contrave and shouldn't be taken in people who have seizure disorders. The drug can also raise blood pressure levels and heart rate, and must not be used in people who have a history of cardiac event or stroke in the earlier six months. Blood pressure and pulse should also be measured before starting the drug and throughout therapy with the drug. The FDA also warned that Contrave can raise blood pressure level and heartbeat and must not be used in patients with uncontrolled high blood pressure, along with by a person with heart-related and cerebrovascular (circulation dysfunction impacting the mind) disease. Patients which has a history of cardiac arrest or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded through the clinical trials. Those taking Contrave needs to have their heart-rate and pulse monitored regularly. In addition, considering that the compound includes bupropion, Contrave comes using a boxed warning to alert health care professionals and patients for the increased likelihood of suicidal thoughts and behaviors associated with antidepressant drugs. The warning also notes that serious neuropsychiatric events are already reported in patients taking bupropion for quitting smoking. "There were no signs and symptoms of depression or suicidal thoughts in trial participants," said Fujioka.