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What if you are a problem drinker or alcoholic, as well as a medical professional could give you a drug to take away your urge to drink—while you are still permitted to continue drinking? Advocates of the treatment approach, referred to as Sinclair method, claim you'd likely experience no withdrawal symptoms. According to proponents, after three to four months about the medication, all while still being able to continue to drink, you'd experience diminished cravings as well as find that your urge to drink disappears altogether. Using two separate drugs to lose weight can be very effective you can find combinations as you're watching FDA now awaiting approval. When dealing with weight-loss and the people who go through it you should err on the side of caution and allow FDA do its job and demand some study be done in order that the public understands the side effects and hazards of the medications before we bring them. Keep in mind that drug companies will be in business to generate money and that they would say anything to keep people on the medications. Researchers discovered that participants taking this drug for a year, dropped a few pounds within one month and have kept the extra weight off through the entire 56 weeks with the study. Contrave is really a combination with the drugs naltrexone and bupropion, which generally seems to reflect a brand new trend of weight-loss drugs which might be made up of more than one active ingredient, which may make them far better and safer. Combo-pilling is the newest fad or in addition to this the newest into the future under scrutiny and therefore it is just more publicly known in recent months, comb-pilling for losing weight has been around since the eighties. The biggest reason that utilizing a combination of pills has become popular may be the fact that by right now there are no long term prescription slimming capsules that have been authorized by the FDA other than orlistat. The truly disturbing part is doctors are prescribing these combinations of medications and some of the combinations are actually rejected or have yet to be licensed by the FDA. Seizures are a side effect with Contrave and mustn't be taken in people with seizure disorders. The drug may also raise hypertension and heartrate, and really should not be used in those with a history of heart attack or stroke in the earlier six months. Blood pressure and pulse should also be measured before beginning the drug and throughout therapy while using drug. The FDA also warned that Contrave can raise hypertension and heartbeat and must not used in patients with uncontrolled high blood pressure level, as well as by anyone with heart-related and cerebrovascular (circulatory dysfunction impacting the brain) disease. Patients having a history of cardiac event or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, since the compound includes bupropion, Contrave comes which has a boxed warning to alert medical researchers and patients on the increased risk of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events are actually reported in patients taking bupropion for stop smoking. "This could be the first drug I'm conscious of that targets both the appetite and reward centres in the brain," he explained.