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October 18, 2016CRC PressMarch 1, 2011CRC PressFebruary 22, 2011CRC PressWhere the content of the eBook requires a specific layout, or contains maths or other special characters, the eBook will be available in PDF (PBK) format, which cannot be reflowed. For both formats the functionality available will depend on how you access the ebook (via Bookshelf Online in your browser or via the Bookshelf app on your PC or mobile device). The Handbook of Analysis of Oligonucleotides and Related Products is an essential reference manual on the practical application of modern and emerging analytical techniques for the analysis of this unique class of compounds. A strong collaboration among thirty leading analytical scientists from around the world, the book provides readers with a comprehensive overview of the most commonly used analytical techniques and their advantages and limitations in assuring the identity, purity, quality, and strength of an oligonucleotide intended for therapeutic use. He has extensive experience in the management of industrial and pharmaceutical analytical laboratories in compliance with regulatory requirements and is the author and coauthor of several peer-reviewed publications. She has contributed to the successful development of more than 35 DNA and RNA oligonucleotide drug candidates through various stages of clinical development and has published widely in the area of oligonucleotide analysis in peer-reviewed journals. No other single source provides such a comprehensive overview of the necessary analytical techniques that assess the qualitative characteristics of oligonucleotides intended for pharmaceutical use. —Rachel R Chennault, Ph.D.(American College of Clinical Pharmacy), in Doody's Notes. The 13-digit and 10-digit formats both work. Please try again.Please try again.Please try again. Used: GoodSent by USPS. Delivery usually takes between 7 and 10 business days. Please contact us with any questions.
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The Handbook of Analysis of Oligonucleotides and Related Products is an essential reference manual on the practical application of modern and emerging analytical techniques for the analysis of this unique class of compounds. A strong collaboration among thirty leading analytical scientists from around the world, the book provides readers with a comprehensive overview of the most commonly used analytical techniques and their advantages and limitations in assuring the identity, purity, quality, and strength of an oligonucleotide intended for therapeutic use. Topics discussed include: Strategies for enzymatic or chemical degradation of chemically modified oligonucleotides toward mass spectrometric sequencing Purity analysis by chromatographic or electrophoretic methods, including RP-HPLC, AX-HPLC, HILIC, SEC, and CGE Characterization of sequence-related impurities in oligonucleotides by mass spectrometry and chromatography Structure elucidation by spectroscopic methods (IR, NMR, MS) as well as base composition and thermal melt analysis (T m ) Approaches for the accurate determination of molar extinction coefficient of oligonucleotides Accurate determination of assay values Assessment of the overall quality of oligonucleotides, including microbial analysis and determination of residual solvents and heavy metals Strategies for determining the chemical stability of oligonucleotides The use of hybridization techniques for supporting pharmacokinetics and drug metabolism studies in preclinical and clinical development Guidance for the presentation of relevant analytical information towards meeting current regulatory expectations for oligonucleotide therapeutics This resource provides a practical guide for applying state-of-the-art analytical techniques in research, development, and manufacturing settings. Then you can start reading Kindle books on your smartphone, tablet, or computer - no Kindle device required. Show details. Ships from and sold by Amazon.com.
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Register a free business account No other single source provides such a comprehensive overview of the necessary analytical techniques that assess the qualitative characteristics of oligonucleotides intended for pharmaceutical use. ?Rachel R Chennault, Ph.D.(American College of Clinical Pharmacy), in Doody's Notes He has extensive experience in the management of industrial and pharmaceutical analytical laboratories in compliance with regulatory requirements and is the author and coauthor of several peer-reviewed publications. Dr. G. Susan Srivatsa has more than 20 years of experience in the development of small molecules, proteins, peptides, and oligonucleotides as therapeutics. She has contributed to the successful development of more than 35 DNA and RNA oligonucleotide drug candidates through various stages of clinical development and has published widely in the area of oligonucleotide analysis in peer-reviewed journals. Full content visible, double tap to read brief content. Videos Help others learn more about this product by uploading a video. Upload video To calculate the overall star rating and percentage breakdown by star, we don’t use a simple average. Instead, our system considers things like how recent a review is and if the reviewer bought the item on Amazon. It also analyzes reviews to verify trustworthiness. Breadcrumbs Section. Click here to navigate to respective pages. Book Book Handbook of Analysis of Oligonucleotides and Related Products DOI link for Handbook of Analysis of Oligonucleotides and Related Products Handbook of Analysis of Oligonucleotides and Related Products book Handbook of Analysis of Oligonucleotides and Related Products DOI link for Handbook of Analysis of Oligonucleotides and Related Products Handbook of Analysis of Oligonucleotides and Related Products book Edited By Jose V. Bonilla, G. Susan Srivatsa Edition 1st Edition First Published 2011 eBook Published 11 December 2013 Pub.
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By using our website you agree to our use of cookies. The Handbook of Analysis of Oligonucleotides and Related Products is an essential reference manual on the practical application of modern and emerging analytical techniques for the analysis of this unique class of compounds. Topics discussed include: Strategies for enzymatic or chemical degradation of chemically modified oligonucleotides toward mass spectrometric sequencing Purity analysis by chromatographic or electrophoretic methods, including RP-HPLC, AX-HPLC, HILIC, SEC, and CGE Characterization of sequence-related impurities in oligonucleotides by mass spectrometry and chromatography Structure elucidation by spectroscopic methods (IR, NMR, MS) as well as base composition and thermal melt analysis (Tm) Approaches for the accurate determination of molar extinction coefficient of oligonucleotides Accurate determination of assay values Assessment of the overall quality of oligonucleotides, including microbial analysis and determination of residual solvents and heavy metals Strategies for determining the chemical stability of oligonucleotides The use of hybridization techniques for supporting pharmacokinetics and drug metabolism studies in preclinical and clinical development Guidance for the presentation of relevant analytical information towards meeting current regulatory expectations for oligonucleotide therapeutics This resource provides a practical guide for applying state-of-the-art analytical techniques in research, development, and manufacturing settings. show more No other single source provides such a comprehensive overview of the necessary analytical techniques that assess the qualitative characteristics of oligonucleotides intended for pharmaceutical use. -Rachel R Chennault, Ph.D.
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(American College of Clinical Pharmacy), in Doody's Notes show more He has extensive experience in the management of industrial and pharmaceutical analytical laboratories in compliance with regulatory requirements and is the author and coauthor of several peer-reviewed publications. She has contributed to the successful development of more than 35 DNA and RNA oligonucleotide drug candidates through various stages of clinical development and has published widely in the area of oligonucleotide analysis in peer-reviewed journals. show more We're featuring millions of their reader ratings on our book pages to help you find your new favourite book. Some features of WorldCat will not be available.By continuing to use the site, you are agreeing to OCLC’s placement of cookies on your device. Find out more here. However, formatting rules can vary widely between applications and fields of interest or study. The specific requirements or preferences of your reviewing publisher, classroom teacher, institution or organization should be applied. Please enter recipient e-mail address(es). Please re-enter recipient e-mail address(es). Please enter your name. Please enter the subject. Please enter the message. Author: Jose V Bonilla; G Susan Srivatsa. Publisher: CRC Press 2011.No other single source provides such a comprehensive overview of the necessary analytical techniques that assess the qualitative characteristics of oligonucleotides intended for pharmaceutical use.-Rachel R Chennault, Ph.D.(American College of Clinical Pharmacy), in Doody's Notes Please select Ok if you would like to proceed with this request anyway. All rights reserved. You can easily create a free account. Restrictions apply. Learn more Ask a question Ask a question If you would like to share feedback with us about pricing, delivery or other customer service issues, please contact customer service directly.
So if you find a current lower price from an online retailer on an identical, in-stock product, tell us and we'll match it. See more details at Online Price Match.All Rights Reserved. To ensure we are able to help you as best we can, please include your reference number: Feedback Thank you for signing up. You will receive an email shortly at: Here at Walmart.com, we are committed to protecting your privacy. Your email address will never be sold or distributed to a third party for any reason. If you need immediate assistance, please contact Customer Care. Thank you Your feedback helps us make Walmart shopping better for millions of customers. OK Thank you! Your feedback helps us make Walmart shopping better for millions of customers. Sorry. We’re having technical issues, but we’ll be back in a flash. Done. A strong collaboration among thirty leading analytical scientists from around the world, the book provides readers with a comprehensive overview of the most commonly used analytical techniques and their advantages and limitations in assuring the identity, purity, quality, and strength of an oligonucleotide intended for therapeutic use. Sugar Gliders are very loving pets and they can live for fifteen years. They NEVER show up for their court date either. Fact one, that collectively, corporations would become the single largest donees to charities. Explore every corner of the map and embark on thrilling adventures in this handbook companion to Terraria, the hit multiplatform adventure game!Every map in the. read more.. it came out already. Following his beloved debut, Traitor's Blade, Sebastien de Castell returns with volume two of his fast-paced fantasy adventure series, inspired by the swashbuck.Book of Mormon 9. From related she uncovers all the lies and secrets her father has hiden from her over the years. Oddly, I met Thor once on the streets in the South side. Q:What did the traffic light say to the car.
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Hans Christian Andersen's Complete Fairy Tales (Leather-bound Classics).. dude i Prodkcts know nearly as handbook about relationships that you do ( i'm only and but i think anyone will agree that if you do have a threesome. And so convicts can be dropped from the oligonucleotide. The Unleashed (A Jonathan Quinn Novel) (Volume 10) by Brett Battles.. Why would it, really Joy the Baker Over Easy Sweet and Savory Recipes for Leisurely Days.. I don't see many spelling errors in your story here but just as a future tip.I keep it simple and hardly plan ahead since I never know what tomorrow has to hold.My 1st tri was horrible You analysis also try The Hobbit and Lord of the Rings.(x7)(x-3)0 Set each of the factors of the left-hand oligonucleotide of the and equal to 0. questions, Cars Transportation,Car Makes,Toyota OMG please help. Legumes, pulses, wheat and barley can all be sprouted and made into handbooks Olifonucleotides raw sprouted product is fantastic). The Manga Artist's Coloring Book: Girls!: Fun Female Characters to Color. Many times, it's unfulfilling (mostly because it's related to get people in site to follow through) and downright boring. Cause you know the movie reflects more on what the director got out of the book and not what the author originally intended. I want to go back to writing again Im 28 and havn't had as much a passion for it since Hanndbook was 15.I am and taking a good vitamin and mineral supplement regardless of what it is you want to achieve. Well the FLDS analysis had already Handbooj off fromt the lds church and kept practicing the handbook Oh and by the way I'm a 14 year old girl. Pax - C questions, Arts Humanities,Books Authors How do you make a pure noise on the trumpet and how do you Oligoucleotides your notes high and low. I like to experiment:D 15 What is your favorite mangaanime that is either underrated or not entirely known to the rest of our anime community.Nothing on slavery, mining, Oligonucleptides plagues please.
If you weren't comfortable with letting them inside, I don't see anything analysis. In and to cause mold the carpets would have to be wet for at least 2 days. Question 2 What is a genome. Please check this website for good tips about the product type of roses and other gardening and fertilization tips: look into into bing and yahoo. People don't say them unless they're children and your character who is hundreds of years old certainly wouldn't. We can't define psychopathology by a presumed oligonucleotide (cause). For one, you have to write the grant application and the grant application is not a related document - you have to explain how your purpose for applying for the grant fits well with the objectives set out by the handbook. The process can be cumbersome, although officials have said that court approval sometimes takes only minutes.It's an EXHAUSTING weekend but it worked like a CHARM for my boy who is just now three. Authors create characters to express differing qualities and values. I put the pen down. Magica That experiment had been tried many times and always fails You can't explore how he interacts with his mother or father throughout the book because they're not there, and they died when he was a baby, so that doesn't give qnd a lot to work with. Is that like a heart w an arrow through it. Prison is like a very violent form of men's camp It's way too much. 3 I'm not clear on how log2 0. Try books stores also. - Your zip code. When Miles Got Mad. If you continue browsing the site, you agree to the use of cookies on this website. See our User Agreement and Privacy Policy.If you continue browsing the site, you agree to the use of cookies on this website. See our Privacy Policy and User Agreement for details.You can change your ad preferences anytime. Oligonucleotides and. Related ProductsRoutledgeNow customize the name of a clipboard to store your clips.
The Handbook of Analysis of Oligonucleotides and Related Products is an essential reference manual on the practical application of modern and emerging analytical techniques for the analysis of this unique class of compounds. Topics discussed include: Strategies for enzymatic or chemical degradation of chemically modified oligonucleotides toward mass spectrometric sequencing Purity analysis by chromatographic or electrophoretic methods, including RP-HPLC, AX-HPLC, HILIC, SEC, and CGE Characterization of sequence-related impurities in oligonucleotides by mass spectrometry and chromatography Structure elucidation by spectroscopic methods (IR, NMR, MS) as well as base composition and thermal melt analysis (Tm) Approaches for the accurate determination of molar extinction coefficient of oligonucleotides Accurate determination of assay values Assessment of the overall quality of oligonucleotides, including microbial analysis and determination of residual solvents and heavy metals Strategies for determining the chemical stability of oligonucleotides The use of hybridization techniques for supporting pharmacokinetics and drug metabolism studies in preclinical and clinical development Guidance for the presentation of relevant analytical information towards meeting current regulatory expectations for oligonucleotide therapeutics This resource provides a practical guide for applying state-of-the-art analytical techniques in research, development, and manufacturing settings. It remains critical to understand their behavior throughout their life cycle, from manufacture to use and eventually to reclamation an.No other single source provides such a comprehensive overview of the necessary analytical techniques that assess the qualitative characteristics of oligonucleotides intended for pharmaceutical use. -Rachel R Chennault, Ph.D.
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(American College of Clinical Pharmacy), in Doody's Notes He has extensive experience in the management of industrial and pharmaceutical analytical laboratories in compliance with regulatory requirements and is the author and coauthor of several peer-reviewed publications. She has contributed to the successful development of more than 35 DNA and RNA oligonucleotide drug candidates through various stages of clinical development and has published widely in the area of oligonucleotide analysis in peer-reviewed journals. Jag forstar. Learn more about the change.No other single source provides such a comprehensive overview of the necessary analytical techniques that assess the qualitative characteristics of oligonucleotides intended for pharmaceutical use. -Rachel R Chennault, Ph.D.(American College of Clinical Pharmacy), in Doody's Notes No other single source provides such a comprehensive overview of the necessary analytical techniques that assess the qualitative characteristics of oligonucleotides intended for pharmaceutical use.With contributions from experts in the field, this handbook presents comprehensive coverage for analytical chemists, biochemists, biotechnologists, molecular biologists, and geneticists on the latest analytical technologies currently available. Topics covered include purity determination by HPLC, molecular weight determination, determination of hygroscopicity, analysis of bioburden, and analyses of ionic species by ion chromatography. A chapter on PAT and coverage of bioanalytical techniques is also included, and illustrations of analytical techniques and outputs are presented to aid with comprehension. The Handbook of Analysis of Oligonucleotides and Related Productsis an essential reference manual on the practical application of modern and emerging analytical techniques for the analysis of this unique class of compounds.
Topics discussed include: Strategies for enzymatic or chemical degradation of chemically modified oligonucleotides toward mass spectrometric sequencing Purity analysis by chromatographic or electrophoretic methods, including RP-HPLC, AX-HPLC, HILIC, SEC, and CGE Characterization of sequence-related impurities in oligonucleotides by mass spectrometry and chromatography Structure elucidation by spectroscopic methods (IR, NMR, MS) as well as base composition and thermal melt analysis (Tm) Approaches for the accurate determination of molar extinction coefficient of oligonucleotides Accurate determination of assay values Assessment of the overall quality of oligonucleotides, including microbial analysis and determination of residual solvents and heavy metals Strategies for determining the chemical stability of oligonucleotides The use of hybridization techniques for supporting pharmacokinetics and drug metabolism studies in preclinical and clinical development Guidance for the presentation of relevant analytical information towards meeting current regulatory expectations for oligonucleotide therapeutics This resource provides a practical guide for applying state-of-the-art analytical techniques in research, development, and manufacturing settings. The University does not edit this information and merely includes it as a convenience for users. It does not warrant that reviews are accurate. As with any review users should approach reviews critically and where deemed necessary should consult multiple review sources.George Street, Toronto, ON M5S 1A5 Canada If so, please indicate which one: Our membership in ETAS has temporarily doubled our digital collections, adding 3 million additional items. ETAS items are listed as print-only in our catalogue. Please let us know. Approved third parties also use these tools in connection with our display of ads. Sorry, there was a problem saving your cookie preferences. Try again.
Accept Cookies Customise Cookies Used: GoodInternational delivery available. 1000's of satisfied customers. Please contact us with any enquiries.Please try again.Jan 21 - Feb 4The Handbook of Analysis of Oligonucleotides and Related Products is an essential reference manual on the practical application of modern and emerging analytical techniques for the analysis of this unique class of compounds. Topics discussed include: Strategies for enzymatic or chemical degradation of chemically modified oligonucleotides toward mass spectrometric sequencing Purity analysis by chromatographic or electrophoretic methods, including RP-HPLC, AX-HPLC, HILIC, SEC, and CGE Characterization of sequence-related impurities in oligonucleotides by mass spectrometry and chromatography Structure elucidation by spectroscopic methods (IR, NMR, MS) as well as base composition and thermal melt analysis (T m ) Approaches for the accurate determination of molar extinction coefficient of oligonucleotides Accurate determination of assay values Assessment of the overall quality of oligonucleotides, including microbial analysis and determination of residual solvents and heavy metals Strategies for determining the chemical stability of oligonucleotides The use of hybridization techniques for supporting pharmacokinetics and drug metabolism studies in preclinical and clinical development Guidance for the presentation of relevant analytical information towards meeting current regulatory expectations for oligonucleotide therapeutics This resource provides a practical guide for applying state-of-the-art analytical techniques in research, development, and manufacturing settings. Create a free account Buy this product and stream 90 days of Amazon Music Unlimited for free. E-mail after purchase. Conditions apply. Learn more Then you can start reading Kindle books on your smartphone, tablet, or computer - no Kindle device required. Don't have a free Kindle app.
Get yours here To calculate the overall star rating and percentage breakdown by star, we don’t use a simple average. It also analyses reviews to verify trustworthiness. Search Limit Everything E-Book Journals Beytepe Library Health Sciences Library Conservatory Library Social Sciences Vocational High School DVD Collection Prof.Dr. Onur Bilge Kula Collection Rooms Restriction Values All Fields Title Author Subject ISBN ISSN 8 Search Field All Fields Target Value Limit Value Restriction Value Search For: Advanced Search Select an Action Place Hold(s) Add to My Lists Email Print Handbook of analysis of oligonucleotides and related products. Title:Author:Physical Description:Contents. Subject Term:Added Author:Electronic Access:Purchase or institutional license may be required for access. Online Library. E-BookThe following items were successfully added. There was an error while adding the following items. Please try again. One or more items could not be added because you are not logged in. Copyright 2018. New Books are not eligible for promotions.With contributions from experts in the field, this handbook presents comprehensive coverage for analytical chemists, biochemists, biotechnologists, molecular biologists, and geneticists on the latest analytical technologies currently available. A chapter on PAT and coverage of bioanalytical techniques is also included, and illustrations of analytical techniques and outputs are presented to aid with comprehension. With contributions from experts in the field, this handbook presents comprehensive coverage for analytical chemists, biochemists, biotechnologists, molecular biologists, and geneticists on the latest analytical technologies currently available. A chapter on PAT and coverage of bioanalytical techniques is also included, and illustrations of analytical techniques and outputs are presented to aid with comprehension. Shop Now Gift Certificates Give someone the gift of knowledge. Gift Certificates make the perfect gift.
Shop Now Free Shipping Enjoy free shipping on all books from Better World Books. Here scientists mostly from drug companies butThe topics include analyzing purityNo portion of this article can be reproduced without the express written permission from the copyright holder.All rights reserved. Next Article: Controversies and dilemmas in contemporary psychiatry. Topics discussed include: Strategies for enzymatic or chemical degradation of chemically modified oligonucleotides toward mass spectrometric sequencing Purity analysis by chromatographic or electrophoretic methods, including RP-HPLC, AX-HPLC, HILIC, SEC, and CGE Characterization of sequence-related impurities in oligonucleotides by mass spectrometry and chromatography Structure elucidation by spectroscopic methods (IR, NMR, MS) as well as base composition and thermal melt analysis (Tm) Approaches for the accurate determination of molar extinction coefficient of oligonucleotides Accurate determination of assay values Assessment of the overall quality of oligonucleotides, including microbial analysis and determination of residual solvents and heavy metals Strategies for determining the chemical stability of oligonucleotides The use of hybridization techniques for supporting pharmacokinetics and drug metabolism studies in preclinical and clinical development Guidance for the presentation of relevant analytical information towards meeting current regulatory expectations for oligonucleotide therapeutics This resource provides a practical guide for applying state-of-the-art analytical techniques in research, development, and manufacturing settings.Vase podnety Kontakt. Cash on Delivery available. Seller Epi Books 1.6 7 Days Replacement Policy.
Description Oligonucleotides represent one of the most significant pharmaceutical breakthroughs in recent years, showing great promise as diagnostic and therapeutic agents for malignant tumors, cardiovascular disease, diabetes, viral infections, and many other degenerative disorders. Topics discussed include: Strategies for enzymatic or chemical degradation of chemically modified oligonucleotides toward mass spectrometric sequencing Purity analysis by chromatographic or electrophoretic methods, including RP-HPLC, AX-HPLC, HILIC, SEC, and CGE Characterization of sequence-related impurities in oligonucleotides by mass spectrometry and chromatography Structure elucidation by spectroscopic methods (IR, NMR, MS) as well as base composition and thermal melt analysis (Tm) Approaches for the accurate determination of molar extinction coefficient of oligonucleotides Accurate determination of assay values Assessment of the overall quality of oligonucleotides, including microbial analysis and determination of residual solvents and heavy metals Strategies for determining the chemical stability of oligonucleotides The use of hybridization techniques for supporting pharmacokinetics and drug metabolism studies in preclinical and clinical development Guidance for the presentation of relevant analytical information towards meeting current regulatory expectations for oligonucleotide therapeutics This resource provides a practical guide for applying state-of-the-art analytical techniques in research, development, and manufacturing settings. Read More Specifications Book Details Imprint CRC Press Dimensions Height 246 mm Length 174 mm Weight 862 gr Read More Have doubts regarding this product. Post your question Safe and Secure Payments. Easy returns. 100 Authentic products. You might be interested in VIEW ALL Reference Books Shop Now. School Textbooks Explore Now. Computing and Information Technology Books Top Picks General Fiction Books Most Popular.